Deposition of docosahexaenoic acid (DHA) is limited in forebrain of young obese fa/ fa Zucker rats fed a diet high in α-linolenic acid but devoid of DHA

Docosahexaenoic acid (DHA) is required for neurotransmitter synthesis and learning. Conversion of α-linolenic acid (ALA) to DHA is considered adequate to support brain function in youth, but it is unknown if brain DHA can be maintained in insulin resistant states. This study investigated brain fatty...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2011-09, Vol.22 (9), p.835-842
Hauptverfasser:	Zhao, Jinping, Gillam, Melani E, Taylor, Carla G, Weiler, Hope A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue adiposity alpha-Linolenic Acid - administration & dosage Animals Biological and medical sciences Brain correlation desaturase DHA Diet Diets Docosahexaenoic acid Docosahexaenoic Acids - administration & dosage Docosahexaenoic Acids - metabolism Fatty Acid Desaturases - metabolism Fatty acids Feeding. Feeding behavior Forebrain Fundamental and applied biological sciences. Psychology genotype Genotypes Homeostasis Hyperinsulinemia Insulin Insulin Resistance Learning Linoleic acid linseed Male menhaden Neurotransmitters Obesity Obesity - metabolism Oil Prosencephalon - metabolism Rats Rats, Zucker safflower oil stearoyl-CoA desaturase Vertebrates: anatomy and physiology, studies on body, several organs or systems Young Zucker rats youth α-linolenic acid
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