Asymmetric [C + NC + CC] Coupling Entry to the Naphthyridinomycin Natural Product Family: Formal Total Synthesis of Cyanocycline A and Bioxalomycin β2

A full account of our [C + NC + CC] coupling approach to the naphthyridinomycin family of natural products is presented, culminating in formal total syntheses of cyanocycline A and bioxalomycin β2. The key complexity-building reaction in the synthesis involves the AgI-catalyzed endo-selective [C + N...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of organic chemistry 2011-07, Vol.76 (13), p.5283-5294
Hauptverfasser:	Garner, Philip, Kaniskan, H. Ümit, Keyari, Charles M, Weerasinghe, Laksiri
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Factors - chemical synthesis Biological Factors - chemistry Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms Heterocyclic compounds with only one n hetero atom and condensed derivatives Molecular Conformation Naphthyridines - chemical synthesis Naphthyridines - chemistry Organic chemistry Oxazoles - chemical synthesis Oxazoles - chemistry Preparations and properties Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!