Multi-objective optimization of glycopeptide antibiotic production in batch and fed batch processes

Fermentation optimization involves potentially conflicting multiple objectives such as product concentration and production media cost. Simultaneous optimization of these objectives would result in a multiobjective optimization problem, which is characterized by a set of multiple solutions, knows as...

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Veröffentlicht in:	Bioresource technology 2011-07, Vol.102 (13), p.6951-6958
Hauptverfasser:	Maiti, Soumen K., Lantz, Anna Eliasson, Bhushan, Mani, Wangikar, Pramod P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales - drug effects Actinomycetales - growth & development Amycolatopsis Anti-Bacterial Agents - biosynthesis Antibiotics Batch Biological and medical sciences Bioreactors - microbiology Biotechnology - methods Carbon - pharmacology Fed batch Fermentation - drug effects Flexibility Fundamental and applied biological sciences. Psychology Glycopeptide antibiotic Glycopeptides Glycopeptides - biosynthesis Mathematical models Media Multi-objective optimization Optimization Pareto optimal Pareto optimality Reproducibility of Results
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