Nanoparticle-based immunosensor with apoferritin templated metallic phosphate label for quantification of phosphorylated acetylcholinesterase

A new sandwich-like electrochemical immunosensor has been developed for quantification of organophosphorylated acetylcholinesterase (OP-AChE), an exposure biomarker of organophosphate pesticides and nerve agents. Zirconia nanoparticles (ZrO 2 NPs) were anchored on a screen printed electrode (SPE) to...

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Veröffentlicht in:	Biosensors & bioelectronics 2011-05, Vol.26 (9), p.3857-3863
Hauptverfasser:	Du, Dan, Chen, Aiqiong, Xie, Yunying, Zhang, Aidong, Lin, Yuehe
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase Acetylcholinesterase - chemistry Acetylcholinesterase - isolation & purification Acetylcholinesterase - metabolism ADDUCTS AFFINITY Amplification Antibodies Apoferritin Apoferritins - chemistry ATOMIC AND MOLECULAR PHYSICS Biological and medical sciences Biomarker Biosensing Techniques Biosensors Biotechnology DETECTION Electrochemistry ELECTRODES Environmental Exposure Fundamental and applied biological sciences. Psychology Immunoassay - methods Immunosensor Immunosensors LEAD IONS Metals - chemistry Methods. Procedures. Technologies MICROBALANCES Microorganisms MONITORING Nanomaterials Nanoparticle Nanoparticles - chemistry Nanostructure NERVES Organophosphate pesticides PESTICIDES Pesticides - adverse effects PHOSPHATES Phosphates - chemistry Phosphorylation PHYSICS OF ELEMENTARY PARTICLES AND FIELDS QUARTZ SCREENS SENSITIVITY SOLAR PROTONS Various methods and equipments Zirconium dioxide
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