Exploratory drug safety: A discovery strategy to reduce attrition in development

Identification of novel new molecules which hold the greatest promise of safe and effective therapies remains a continuous challenge to the pharmaceutical industry. This has led the industry to implement strategies for identification of the most promising candidates during the discovery phase and fo...

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Veröffentlicht in:	Journal of pharmacological and toxicological methods 2009-07, Vol.60 (1), p.69-78
Hauptverfasser:	Bass, Alan S., Cartwright, Mark E., Mahon, Craig, Morrison, Richard, Snyder, Ronald, McNamara, Paul, Bradley, Prudence, Zhou, Ying-Ying, Hunter, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse events Animals Attrition Discovery and development strategy Discovery toxicology Drug Discovery Drug Evaluation, Preclinical Drug Industry Drug-Related Side Effects and Adverse Reactions Exploratory drug safety Genetic toxicology Pharmaceutical Preparations - metabolism Research Design Safety pharmacology Toxicology - methods
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