Validity of perfusion parameters obtained using the modified Tofts model: A simulation study

The two‐compartment Tofts model (2CTM) has had widespread use in research and clinical practice. It assumes there is no broadening associated with the bolus transit through the capillary bed of the tissue under study. This assumption is often violated, with consequences that are hard to predict intu...

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Veröffentlicht in:	Magnetic resonance in medicine 2011-05, Vol.65 (5), p.1491-1497
Hauptverfasser:	Luypaert, Robert, Sourbron, Steven, de Mey, Johan
Format:	Artikel
Sprache:	eng
Schlagworte:	Bolus‐tracking Computer Simulation Contrast Media - pharmacokinetics Hemodynamics Magnetic Resonance Imaging - methods Models, Biological MRI perfusion permeability Tofts model
Online-Zugang:	Volltext
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