Proteomics analysis of liver samples from puffer fish Takifugu rubripes exposed to excessive fluoride: An insight into molecular response to fluorosis

Comparative proteomics was performed to identify proteins in the liver of Takifugu rubripes in response to excessive fluoride exposure. Sixteen fish were randomly divided into a control group and an experimental group. The control group was raised in soft water alone (F− = 0.4 mg/L), and the experim...

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Veröffentlicht in:	Journal of biochemical and molecular toxicology 2010-01, Vol.24 (1), p.21-28
Hauptverfasser:	Lu, Jian, Zheng, Jianzhou, Liu, Haijun, Li, Jun, Xu, Qinggang, Chen, Keping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Databases, Protein Down-Regulation - drug effects Electrophoresis, Gel, Two-Dimensional Fish Proteins - chemistry Fish Proteins - metabolism Fluoride Poisoning - metabolism Fluorides - toxicity Fluorosis Image Processing, Computer-Assisted Liver - drug effects Liver - metabolism Liver Proteome MALDI-TOF-MS Proteomics - methods Random Allocation Sodium Fluoride - administration & dosage Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Takifugu Takifugu - metabolism Takifugu rubripes Tandem Mass Spectrometry Two-Dimensional Electrophoresis Up-Regulation - drug effects
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