The re-emergence of pertussis in Tunisia
The authors had for aim to analyze pertussis epidemiology in Tunisia by studying nasopharyngeal specimens of infants hospitalized in Tunis. Between march 2007 and march 2008, clinical nasopharyngeal samples were collected from infants with a suspected diagnosis of whooping cough, pertussoid cough, o...
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| Veröffentlicht in: | Médecine et maladies infectieuses 2011-02, Vol.41 (2), p.97-101 |
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| creator | Zouari, A Smaoui, H Njamkepo, E Mnif, K Ben Jaballah, N Bousnina, S Barsaoui, S Sammoud, A Ben Becher, S Guiso, N Kechrid, A |
| description | The authors had for aim to analyze pertussis epidemiology in Tunisia by studying nasopharyngeal specimens of infants hospitalized in Tunis.
Between march 2007 and march 2008, clinical nasopharyngeal samples were collected from infants with a suspected diagnosis of whooping cough, pertussoid cough, or pertussis-like syndrome, admitted at the Tunis children's hospital. The laboratory diagnostic criteria were culture isolation of Bordetella species on Bordet-Gengou medium and real-time PCR.
Fifty-nine percent of the 74 investigated children with suspected pertussis were less than two months of age. The diagnosis of pertussis was proved positive by real-time PCR for 41%. Culture was negative in all cases.
Whooping cough is still prevalent in Tunisia despite an important vaccination coverage. Real-time PCR is an invaluable tool for the rapid diagnosis of pertussis, however culture must also be associated. |
| doi_str_mv | 10.1016/j.medmal.2010.11.008 |
| format | Article |
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Between march 2007 and march 2008, clinical nasopharyngeal samples were collected from infants with a suspected diagnosis of whooping cough, pertussoid cough, or pertussis-like syndrome, admitted at the Tunis children's hospital. The laboratory diagnostic criteria were culture isolation of Bordetella species on Bordet-Gengou medium and real-time PCR.
Fifty-nine percent of the 74 investigated children with suspected pertussis were less than two months of age. The diagnosis of pertussis was proved positive by real-time PCR for 41%. Culture was negative in all cases.
Whooping cough is still prevalent in Tunisia despite an important vaccination coverage. Real-time PCR is an invaluable tool for the rapid diagnosis of pertussis, however culture must also be associated.</description><identifier>ISSN: 0399-077X</identifier><identifier>EISSN: 1769-6690</identifier><identifier>DOI: 10.1016/j.medmal.2010.11.008</identifier><identifier>PMID: 21215539</identifier><language>fre</language><publisher>France</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Bacteriological Techniques ; Bordetella ; Bordetella pertussis - genetics ; Bordetella pertussis - growth & development ; Bordetella pertussis - isolation & purification ; Computer Systems ; Disease Outbreaks ; DNA, Bacterial - analysis ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Nasopharynx - microbiology ; Pertussis Vaccine ; Polymerase Chain Reaction ; Tunisia - epidemiology ; Vaccination - utilization ; Whooping Cough - drug therapy ; Whooping Cough - epidemiology ; Whooping Cough - prevention & control</subject><ispartof>Médecine et maladies infectieuses, 2011-02, Vol.41 (2), p.97-101</ispartof><rights>Copyright © 2010 Elsevier Masson SAS. All rights reserved.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21215539$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zouari, A</creatorcontrib><creatorcontrib>Smaoui, H</creatorcontrib><creatorcontrib>Njamkepo, E</creatorcontrib><creatorcontrib>Mnif, K</creatorcontrib><creatorcontrib>Ben Jaballah, N</creatorcontrib><creatorcontrib>Bousnina, S</creatorcontrib><creatorcontrib>Barsaoui, S</creatorcontrib><creatorcontrib>Sammoud, A</creatorcontrib><creatorcontrib>Ben Becher, S</creatorcontrib><creatorcontrib>Guiso, N</creatorcontrib><creatorcontrib>Kechrid, A</creatorcontrib><title>The re-emergence of pertussis in Tunisia</title><title>Médecine et maladies infectieuses</title><addtitle>Med Mal Infect</addtitle><description>The authors had for aim to analyze pertussis epidemiology in Tunisia by studying nasopharyngeal specimens of infants hospitalized in Tunis.
Between march 2007 and march 2008, clinical nasopharyngeal samples were collected from infants with a suspected diagnosis of whooping cough, pertussoid cough, or pertussis-like syndrome, admitted at the Tunis children's hospital. The laboratory diagnostic criteria were culture isolation of Bordetella species on Bordet-Gengou medium and real-time PCR.
Fifty-nine percent of the 74 investigated children with suspected pertussis were less than two months of age. The diagnosis of pertussis was proved positive by real-time PCR for 41%. Culture was negative in all cases.
Whooping cough is still prevalent in Tunisia despite an important vaccination coverage. Real-time PCR is an invaluable tool for the rapid diagnosis of pertussis, however culture must also be associated.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bacteriological Techniques</subject><subject>Bordetella</subject><subject>Bordetella pertussis - genetics</subject><subject>Bordetella pertussis - growth & development</subject><subject>Bordetella pertussis - isolation & purification</subject><subject>Computer Systems</subject><subject>Disease Outbreaks</subject><subject>DNA, Bacterial - analysis</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Nasopharynx - microbiology</subject><subject>Pertussis Vaccine</subject><subject>Polymerase Chain Reaction</subject><subject>Tunisia - epidemiology</subject><subject>Vaccination - utilization</subject><subject>Whooping Cough - drug therapy</subject><subject>Whooping Cough - epidemiology</subject><subject>Whooping Cough - prevention & control</subject><issn>0399-077X</issn><issn>1769-6690</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAUhYMoTh39ByLd6ab1Jmlvk6UM4wMG3FRwV9r0Rjv0ZdIu_Pd2cFy7OnD4OAc-xq45xBw43u_jjuqubGMBh4rHAOqEBTxDHSFqOGUBSK0jyLL3Fbvwfg8gDuw5WwkueJpKHbC7_JNCRxF15D6oNxQONhzJTbP3jQ-bPsznvvFNecnObNl6ujrmmr09bvPNc7R7fXrZPOyikWdiijCVIIG41FxalapUyMpimqAlww1qkRmDCdW2stIIrRVUlKExldIJIdRyzW5_d0c3fM3kp6JrvKG2LXsaZl8otRwkCvT_JAqBGjku5M2RnKtFWjG6pivdd_GnQf4AK49e5A</recordid><startdate>201102</startdate><enddate>201102</enddate><creator>Zouari, A</creator><creator>Smaoui, H</creator><creator>Njamkepo, E</creator><creator>Mnif, K</creator><creator>Ben Jaballah, N</creator><creator>Bousnina, S</creator><creator>Barsaoui, S</creator><creator>Sammoud, A</creator><creator>Ben Becher, S</creator><creator>Guiso, N</creator><creator>Kechrid, A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>201102</creationdate><title>The re-emergence of pertussis in Tunisia</title><author>Zouari, A ; 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Between march 2007 and march 2008, clinical nasopharyngeal samples were collected from infants with a suspected diagnosis of whooping cough, pertussoid cough, or pertussis-like syndrome, admitted at the Tunis children's hospital. The laboratory diagnostic criteria were culture isolation of Bordetella species on Bordet-Gengou medium and real-time PCR.
Fifty-nine percent of the 74 investigated children with suspected pertussis were less than two months of age. The diagnosis of pertussis was proved positive by real-time PCR for 41%. Culture was negative in all cases.
Whooping cough is still prevalent in Tunisia despite an important vaccination coverage. Real-time PCR is an invaluable tool for the rapid diagnosis of pertussis, however culture must also be associated.</abstract><cop>France</cop><pmid>21215539</pmid><doi>10.1016/j.medmal.2010.11.008</doi><tpages>5</tpages></addata></record> |
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| ispartof | Médecine et maladies infectieuses, 2011-02, Vol.41 (2), p.97-101 |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Anti-Bacterial Agents - therapeutic use Bacteriological Techniques Bordetella Bordetella pertussis - genetics Bordetella pertussis - growth & development Bordetella pertussis - isolation & purification Computer Systems Disease Outbreaks DNA, Bacterial - analysis Female Humans Infant Infant, Newborn Male Nasopharynx - microbiology Pertussis Vaccine Polymerase Chain Reaction Tunisia - epidemiology Vaccination - utilization Whooping Cough - drug therapy Whooping Cough - epidemiology Whooping Cough - prevention & control |
| title | The re-emergence of pertussis in Tunisia |
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