Titanium surface topography affects collagen biosynthesis of adherent cells

Abstract Collagen-dependent microstructure and physicochemical properties of newly formed bone around implant surfaces represent key determinants of implant biomechanics. This study investigated the effects of implant surface topography on collagen biosynthesis of adherent human mesenchymal stem cel...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2011-09, Vol.49 (3), p.463-472
Hauptverfasser:	Mendonça, Daniela B.S, Miguez, Patrícia A, Mendonça, Gustavo, Yamauchi, Mitsuo, Aragão, Francisco J.L, Cooper, Lyndon F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biglycan - genetics Biglycan - metabolism Biological and medical sciences Cell Adhesion - physiology Cells, Cultured Collagen Type I - biosynthesis Collagen Type I - genetics Dystroglycans - genetics Dystroglycans - metabolism Extracellular Matrix - chemistry Fundamental and applied biological sciences. Psychology HSP47 Heat-Shock Proteins - genetics HSP47 Heat-Shock Proteins - metabolism Humans Matrix Metalloproteinases - genetics Matrix Metalloproteinases - metabolism Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - physiology Orthopedics Osteogenesis - physiology Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase - genetics Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase - metabolism Procollagen-Proline Dioxygenase - genetics Procollagen-Proline Dioxygenase - metabolism Protein Isoforms - genetics Protein Isoforms - metabolism Protein-Lysine 6-Oxidase - genetics Protein-Lysine 6-Oxidase - metabolism Surface Properties Tissue Inhibitor of Metalloproteinases - genetics Tissue Inhibitor of Metalloproteinases - metabolism Titanium - chemistry Transforming Growth Factor beta1 - genetics Transforming Growth Factor beta1 - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems
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