Analysis of RhCE variants among 806 individuals in France: considerations for transfusion safety, with emphasis on patients with sickle cell disease

BACKGROUND: DNA testing has enabled the documenting of numerous variants of RHCE alleles, especially in individuals of African origin. The risk for production of clinically significant alloantibodies to Rh antigens of patients carrying variant RHCE alleles has led us to analyze the different RhCE va...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2011-06, Vol.51 (6), p.1249-1260
Hauptverfasser:	Pham, Bach-Nga, Peyrard, Thierry, Juszczak, Genevieve, Beolet, Marylise, Deram, Geneviève, Martin-Blanc, Stéphanie, Dubeaux, Isabelle, Roussel, Michèle, Kappler-Gratias, Sandrine, Gien, Dominique, Poupel, Sylvie, Rouger, Philippe, Le Pennec, Pierre-Yves
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Anemia, Sickle Cell - blood Anemia, Sickle Cell - genetics Anemias. Hemoglobinopathies Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Diseases of red blood cells DNA Female France haplotypes Haplotypes - genetics Hematologic and hematopoietic diseases Humans Male Medical sciences molecular biology Pregnancy Rh-Hr Blood-Group System - genetics safety engineering Sequence Analysis, DNA transfusion Transfusion Reaction Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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