Kojic acid biosynthesis in Aspergillus oryzae is regulated by a Zn(II) sub(2Cys) sub(6) transcriptional activator and induced by kojic acid at the transcriptional level
A gene encoding the Zn(II) sub(2Cys) sub(6) transcriptional factor is clustered with two genes involved in biosynthesis of a secondary metabolite, kojic acid (KA), in Aspergillus oryzae. We determined that the gene was essential for KA production and the transcriptional activation of KA biosynthetic...
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| Veröffentlicht in: | Journal of bioscience and bioengineering 2011-07, Vol.112 (1), p.40-43 |
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| container_title | Journal of bioscience and bioengineering |
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| creator | Marui, Junichiro Yamane, Noriko Ohashi-Kunihiro, Sumiko Ando, Tomohiro Terabayashi, Yasunobu Sano, Motoaki Ohashi, Shinichi Ohshima, Eiji Tachibana, Kuniharu Higa, Yoshitaka Nishimura, Marie Koike, Hideaki Machida, Masayuki |
| description | A gene encoding the Zn(II) sub(2Cys) sub(6) transcriptional factor is clustered with two genes involved in biosynthesis of a secondary metabolite, kojic acid (KA), in Aspergillus oryzae. We determined that the gene was essential for KA production and the transcriptional activation of KA biosynthetic genes, which were triggered by the addition of KA. |
| doi_str_mv | 10.1016/j.jbiosc.2011.03.010 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1389-1723 |
| ispartof | Journal of bioscience and bioengineering, 2011-07, Vol.112 (1), p.40-43 |
| issn | 1389-1723 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_883030008 |
| source | Elsevier ScienceDirect Journals |
| subjects | Aspergillus oryzae Kojic acid Secondary metabolites Transcription activation |
| title | Kojic acid biosynthesis in Aspergillus oryzae is regulated by a Zn(II) sub(2Cys) sub(6) transcriptional activator and induced by kojic acid at the transcriptional level |
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