Reduced CSF turnover and decreased ventricular A beta 42 levels are related

The appearance of A beta 42 peptide deposits is admitted to be a key event in the pathogenesis of Alzheimer's disease, although amyloid deposits also occur in aged non-demented subjects. A beta 42 is a degradation product of the amyloid protein precursor (APP). It can be catabolized by several...

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Veröffentlicht in:BMC neuroscience 2011-05, Vol.12, p.42-42
Hauptverfasser: Serot, Jean-Marie, Peltier, Johann, Fichten, Antony, Ledeme, Nelly, Bourgeois, Anne-Marie, Jouanny, Pierre, Toussaint, Patrick, Legars, Daniel, Godefroy, Olivier, Maziere, Jean-Claude
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Sprache:eng
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