Growth factor delivery through electrospun nanofibers in scaffolds for tissue engineering applications

Tissue engineering scaffolds should ideally mimic the natural ECM in structure and function. Electrospun nanofibrous scaffolds are easily fabricated and possess a biomimetic nanostructure. Scaffolds can mimic ECM function by acting as a depot for sustained release of growth factors. bFGF, an importa...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2010-06, Vol.93A (4), p.1539-1550
Hauptverfasser:	Sahoo, Sambit, Ang, Lay Teng, Goh, James Cho-Hong, Toh, Siew-Lok
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences biomimetic scaffolds Biomimetics Biotechnology Cell Proliferation Collagen - chemistry Electrochemistry - methods electrospinning Extracellular Matrix - metabolism Fibroblast Growth Factor 2 - chemistry Fundamental and applied biological sciences. Psychology growth factors Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Kinetics Medical sciences Microscopy, Electron, Scanning - methods Miscellaneous nanofibers Nanofibers - chemistry Nanotechnology - methods Rabbits Reverse Transcriptase Polymerase Chain Reaction Stem Cells - cytology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments tissue engineering Tissue Engineering - methods
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