Challenges in the design and conduct of controlled clinical effectiveness trials in schizophrenia

Background The introduction of antipsychotic medication has been a major advance in the treatment of schizophrenia and allows millions of people to live outside of institutions. It is generally believed that long-acting intramuscular antipsychotic medication is the most effective approach to increas...

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Veröffentlicht in:	Clinical trials (London, England) England), 2011-04, Vol.8 (2), p.196-204
Hauptverfasser:	Rosenheck, Robert A, Krystal, John H, Lew, Robert, Barnett, Paul G, Thwin, Soe Soe, Fiore, Louis, Valley, Danielle, Huang, Grant D, Neal, Carla, Vertrees, Julia E, Liang, Matthew H
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Antipsychotic Agents - administration & dosage Antipsychotic Agents - economics Antipsychotic Agents - therapeutic use Antipsychotics Clinical trials Comparative Effectiveness Research Delayed-Action Preparations - administration & dosage Delayed-Action Preparations - economics Delayed-Action Preparations - therapeutic use Health care expenditures Health care policy Hospitalization Humans Injections, Intramuscular Interviews as Topic Medication Adherence Mental disorders Patient compliance Patient Readmission - economics Psychosis Psychotropic drugs Quality of Life R&D Research & development Risperidone - administration & dosage Risperidone - economics Risperidone - therapeutic use Schizophrenia Schizophrenia - drug therapy Veterans
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