Local secretion/shedding of tumor-derived CD83 molecules as a novel tumor escape mechanism

CD83, a characteristic marker of activated dendritic cells, is also expressed by tumor cell lines from various origins and by primary lung cancers. Here, we show that CD83+ tumor cells (from a primary lung cancer and from an established breast cancer cell line) release in their culture supernatants...

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Veröffentlicht in:	Molecular immunology 2008-07, Vol.45 (12), p.3502-3504
Hauptverfasser:	Baleeiro, R.B., Barbuto, J.A.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - immunology Antigens, Neoplasm - immunology CD83 CD83 Antigen Cell Proliferation Dendritic cells Humans Immunoglobulins - immunology Immunosuppression Lymphocyte Activation Membrane Glycoproteins - immunology T-Lymphocytes - cytology Tumor Cells, Cultured Tumor Escape - immunology Tumor escape mechanisms
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