Proteomic analysis of low- to high-grade astrocytomas reveals an alteration of the expression level of raf kinase inhibitor protein and nucleophosmin

Proteomic approaches have been useful for the identification of aberrantly expressed proteins in complex diseases such as cancer. These proteins are not only potential disease biomarkers, but also targets for therapy. The aim of this study was to identify differentially expressed proteins in diffuse...

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Veröffentlicht in:	Proteomics (Weinheim) 2010-08, Vol.10 (15), p.2812-2821
Hauptverfasser:	Gimenez, Marcela, de Oliveira Souza, Vanessa Cristina, Izumi, Clarice, Barbieri, Manuela R, Chammas, Roger, Oba-Shinjo, Sueli Mieko, Uno, Miyuki, Marie, Suely Kazue Nagahashi, Rosa, José Cesar
Format:	Artikel
Sprache:	eng
Schlagworte:	2-DE Adult Amino Acid Sequence Analytical, structural and metabolic biochemistry Astrocytoma - genetics Astrocytoma - pathology Astrocytomas Biological and medical sciences Biomedicine Brain - metabolism Brain - pathology Brain Neoplasms - genetics Brain Neoplasms - pathology Electrophoresis, Gel, Two-Dimensional Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Neoplastic Gliomas Humans Male Medical sciences Middle Aged Miscellaneous Molecular Sequence Data Neurology Nuclear Proteins - genetics Nuclear Proteins - isolation & purification Nucleophosmin Phosphatidylethanolamine Binding Protein - genetics Phosphatidylethanolamine Binding Protein - isolation & purification Proteins Proteins - genetics Proteins - isolation & purification Proteomics Raf kinase inhibitor protein Tumors of the nervous system. Phacomatoses
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