Enantioselective esterification of ibuprofen with ethanol as reactant and solvent catalyzed by immobilized lipase: experimental and molecular modeling aspects

BACKGROUND: In recent years enantioselective esterification of racemic ibuprofen performed in organic co-solvent media such as isooctane and cyclohexane and catalyzed by lipases, has been proposed as an effective way to increase the concentration of S-ibuprofen in the racemic mixture. In this contri...

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Veröffentlicht in:	Journal of chemical technology and biotechnology (1986) 2009-10, Vol.84 (10), p.1461-1473
Hauptverfasser:	Foresti, María L, Galle, Marianela, Ferreira, María L, Briand, Laura E
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Biological and medical sciences Biotechnology Catalysis Catalytic reactions Chemical engineering Chemistry enantioselective Esterification Ethanol Ethyl alcohol Exact sciences and technology Fundamental and applied biological sciences. Psychology General and physical chemistry Ibuprofen Lipase Mathematical models Media Methods. Procedures. Technologies molecular modeling Others Reactors Solvents Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry Various methods and equipments
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