The expression of tousled kinases in CaP cell lines and its relation to radiation response and DSB repair

BACKGROUND The Tousled‐like kinases (TLKs) function in processes of chromatin assembly, including replication, transcription, repair, and chromosome segregation. TLK1/1B interacts specifically with the chromatin assembly factor Asf1, a histone H3‐H4 chaperone, and with Rad9, a protein involved in DN...

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Veröffentlicht in:	The Prostate 2011-09, Vol.71 (13), p.1367-1373
Hauptverfasser:	Ronald, Sharon, Sunavala-Dossabhoy, Gulshan, Adams, Lisa, Williams, Briana, De Benedetti, Arrigo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences CaP cell lines Cell Line, Tumor DNA Breaks, Double-Stranded DNA Repair Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Male Medical sciences Nephrology. Urinary tract diseases Prostatic Neoplasms - enzymology Prostatic Neoplasms - genetics Prostatic Neoplasms - radiotherapy Protein Kinases - genetics Protein Kinases - physiology Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - physiology Radiation Tolerance radioresistance TLKs expression
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