ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression

Neurotrophins play essential roles in the development, differentiation, and survival of neuronal and nonneuronal cells. Alterations in neurotrophin expression have been implicated in a variety of neurodegenerative disorders. Dysregulation of brain‐derived neurotrophic factor (BDNF) has been implicat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroscience research 2011-10, Vol.89 (10), p.1542-1550
Hauptverfasser:	Su, Chang, Underwood, Wendy, Rybalchenko, Nataliya, Singh, Meharvan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals Animals, Newborn Astrocytes Astrocytes - drug effects Astrocytes - enzymology Astrocytes - pathology Benzamides - pharmacology Brain-derived neurotrophic factor brain-derived neurotrophic factor (BDNF) Brain-Derived Neurotrophic Factor - antagonists & inhibitors Brain-Derived Neurotrophic Factor - biosynthesis Brain-Derived Neurotrophic Factor - genetics Butadienes - pharmacology Cell Line, Tumor Cell survival Cognition Data processing Differentiation ERK1/2 ERK5 Extracellular signal-regulated kinase Glial cells Glioma - enzymology Glioma - pathology Long-term potentiation MAP kinase MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors Mitogen-Activated Protein Kinase 1 - physiology Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors Mitogen-Activated Protein Kinase 3 - physiology Mitogen-Activated Protein Kinase 7 - antagonists & inhibitors Mitogen-Activated Protein Kinase 7 - genetics Mitogen-Activated Protein Kinase 7 - physiology mRNA Nervous system Neurodegenerative diseases Neurons - drug effects Neurons - enzymology Neurons - pathology Neuroprotection Neurotrophins Nitriles - pharmacology Primary Cell Culture Protein Kinase Inhibitors - pharmacology Rats Rats, Sprague-Dawley Signal transduction transcription Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!