Dynamic nonlinearity of lung tissue: frequency dependence and harmonic distortion

Dynamic nonlinearity of lung tissue: frequency dependence and harmonic distortion

Harmonic distortion (HD) is a simple approach to analyze lung tissue nonlinear phenomena. This study aimed to characterize frequency-dependent behavior of HD at several amplitudes in lung tissue strips from healthy rats and its influence on the parameters of linear analysis. Lung strips (n = 17) wer...

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Veröffentlicht in:Journal of applied physiology (1985) 2011-08, Vol.111 (2), p.420-426
Hauptverfasser: ROMERO, Pablo V, FAFFE, Debora S, CANETE, Concepción
Format: Artikel
Sprache:eng
Schlagworte:
Airway Resistance
Algorithms
Animals
Biological and medical sciences
Biomechanical Phenomena
Correlation analysis
Frequencies
Fundamental and applied biological sciences. Psychology
In Vitro Techniques
Linear Models
Lung - physiology
Lungs
Male
Nonlinear Dynamics
Pulmonary Alveoli - physiology
Rats
Rats, Sprague-Dawley
Respiratory Mechanics - physiology
Rodents
Stress, Physiological
Tissues
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Zusammenfassung:Harmonic distortion (HD) is a simple approach to analyze lung tissue nonlinear phenomena. This study aimed to characterize frequency-dependent behavior of HD at several amplitudes in lung tissue strips from healthy rats and its influence on the parameters of linear analysis. Lung strips (n = 17) were subjected to sinusoidal deformation at three different strain amplitudes (Δε) and fixed operational stress (12 hPa) among various frequencies, between 0.03 and 3 Hz. Input HD was
ISSN:8750-7587
1522-1601
DOI:10.1152/japplphysiol.01487.2010