ODORactor: a web server for deciphering olfactory coding

ODORactor is an open access web server aimed at providing a platform for identifying odorant receptors (ORs) for small molecules and for browsing existing OR-ligand pairs. It enables the prediction of ORs from the molecular structures of arbitrary chemicals by integrating two individual functionalit...

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Veröffentlicht in:Bioinformatics 2011-08, Vol.27 (16), p.2302-2303
Hauptverfasser: Liu, Xinyi, Su, Xubo, Wang, Fei, Huang, Zhimin, Wang, Qi, Li, Zhen, Zhang, Ruina, Wu, Lifang, Pan, Yi, Chen, Yingyi, Zhuang, Hanyi, Chen, Guoqiang, Shi, Ting, Zhang, Jian
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container_end_page 2303
container_issue 16
container_start_page 2302
container_title Bioinformatics
container_volume 27
creator Liu, Xinyi
Su, Xubo
Wang, Fei
Huang, Zhimin
Wang, Qi
Li, Zhen
Zhang, Ruina
Wu, Lifang
Pan, Yi
Chen, Yingyi
Zhuang, Hanyi
Chen, Guoqiang
Shi, Ting
Zhang, Jian
description ODORactor is an open access web server aimed at providing a platform for identifying odorant receptors (ORs) for small molecules and for browsing existing OR-ligand pairs. It enables the prediction of ORs from the molecular structures of arbitrary chemicals by integrating two individual functionalities: odorant verification and OR recognition. The prediction of the ORs for several odorants was experimentally validated in the study. In addition, ODORactor features a comprehensive repertoire of olfactory information that has been manually curated from literature. Therefore, ODORactor may provide an effective way to decipher olfactory coding and could be a useful server tool for both basic olfaction research in academia and for odorant discovery in industry. Availability: Freely available at http://mdl.shsmu.edu.cn/ODORactor Contact: jian.zhang@sjtu.edu.cn Supplementary information: Supplementary data are available at Bioinformatics online.
doi_str_mv 10.1093/bioinformatics/btr385
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source Oxford Journals Open Access Collection
subjects Animals
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
General aspects
Humans
Internet
Ligands
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Mice
Odorants
Receptors, Odorant - chemistry
Smell
Software
title ODORactor: a web server for deciphering olfactory coding
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