Update on External Beam Radiation Therapy in Thyroid Cancer
Surgery is the mainstay of treatment for thyroid cancer. The role for external beam radiotherapy (EBRT) as an adjuvant to surgery or as the primary therapy is established in anaplastic thyroid cancer but is controversial in differentiated thyroid cancer and uncertain in medullary thyroid cancer. Thi...
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| Veröffentlicht in: | The journal of clinical endocrinology and metabolism 2011-08, Vol.96 (8), p.2289-2295 |
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| container_title | The journal of clinical endocrinology and metabolism |
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| creator | Brierley, James D |
| description | Surgery is the mainstay of treatment for thyroid cancer. The role for external beam radiotherapy (EBRT) as an adjuvant to surgery or as the primary therapy is established in anaplastic thyroid cancer but is controversial in differentiated thyroid cancer and uncertain in medullary thyroid cancer. This update reviews the recent reported success of combining EBRT with taxanes in anaplastic thyroid cancer. Also discussed are the recent reports from large single institutions that support the recommendations of the American and British Thyroid Associations on the use of EBRT in high-risk differentiated thyroid cancer. Further evidence on the role of EBRT in MTC is discussed. The important advances in the delivery of EBRT using intensity-modulated radiation and image-guided radiation that result in more accurate and potentially more effective radiation therapy with less toxicity are also discussed. |
| doi_str_mv | 10.1210/jc.2011-1109 |
| format | Article |
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The role for external beam radiotherapy (EBRT) as an adjuvant to surgery or as the primary therapy is established in anaplastic thyroid cancer but is controversial in differentiated thyroid cancer and uncertain in medullary thyroid cancer. This update reviews the recent reported success of combining EBRT with taxanes in anaplastic thyroid cancer. Also discussed are the recent reports from large single institutions that support the recommendations of the American and British Thyroid Associations on the use of EBRT in high-risk differentiated thyroid cancer. Further evidence on the role of EBRT in MTC is discussed. 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Feeding behavior</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Malignant tumors</topic><topic>Medical sciences</topic><topic>Radiation</topic><topic>Radiotherapy</topic><topic>Radiotherapy - methods</topic><topic>Radiotherapy - trends</topic><topic>Risk groups</topic><topic>Surgery</topic><topic>taxanes</topic><topic>thyroid cancer</topic><topic>Thyroid Neoplasms - radiotherapy</topic><topic>Thyroid. 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| ispartof | The journal of clinical endocrinology and metabolism, 2011-08, Vol.96 (8), p.2289-2295 |
| issn | 0021-972X 1945-7197 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Adjuvants Biological and medical sciences Carcinoma - radiotherapy Carcinoma, Medullary - radiotherapy Endocrinopathies Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Humans Malignant tumors Medical sciences Radiation Radiotherapy Radiotherapy - methods Radiotherapy - trends Risk groups Surgery taxanes thyroid cancer Thyroid Neoplasms - radiotherapy Thyroid. Thyroid axis (diseases) Toxicity Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology |
| title | Update on External Beam Radiation Therapy in Thyroid Cancer |
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