Increased expression of periostin in vitreous and fibrovascular membranes obtained from patients with proliferative diabetic retinopathy

Preretinal fibrovascular membranes (FVMs) form as a sequela to proliferative diabetic retinopathy (PDR), and their presence can lead to a severe decrease of vision. The purpose of this study was to determine whether periostin, a matricellular protein that plays a role in cell adhesion and migration,...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2011-07, Vol.52 (8), p.5670-5678
Hauptverfasser:	Yoshida, Shigeo, Ishikawa, Keijiro, Asato, Ryo, Arima, Mitsuru, Sassa, Yukio, Yoshida, Ayako, Yoshikawa, Hiroshi, Narukawa, Keisuke, Obika, Satoshi, Ono, Junya, Ohta, Shoichiro, Izuhara, Kenji, Kono, Toshihiro, Ishibashi, Tatsuro
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Actins - metabolism Alternative Splicing - genetics Cell Adhesion - physiology Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Cell Movement - physiology Cells, Cultured Diabetic Retinopathy - genetics Diabetic Retinopathy - pathology Diabetic Retinopathy - surgery Female Humans Male Middle Aged Oligoribonucleotides, Antisense - pharmacology Retinal Pigment Epithelium - pathology Retinal Pigment Epithelium - physiology Up-Regulation - physiology Vitrectomy Vitreous Body - pathology Vitreous Body - physiology Vitreous Body - surgery
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