Low-level C-reactive protein levels exert cytoprotective actions on human podocytes

Background. Albuminuria and elevated C-reactive protein (CRP) levels are common manifestations of many inflammatory diseases. Cardiovascular-based drugs, with secondary anti-inflammatory actions, such as angiotensin-converting enzyme-inhibitors are able to reduce both proteinuria and CRP levels, rai...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2011-08, Vol.26 (8), p.2465-2475
Hauptverfasser:	Pawluczyk, Izabella Z.A., Yang, Bin, Patel, Samita R., Saleem, Moin A., Topham, Peter S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blotting, Western C-Reactive Protein - antagonists & inhibitors C-Reactive Protein - genetics C-Reactive Protein - metabolism Caspase 3 - metabolism Cells, Cultured Culture Media, Conditioned - pharmacology Cytoprotection Emergency and intensive care: renal failure. Dialysis management Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Humans Immunoenzyme Techniques Inflammation Intensive care medicine Interleukin-1beta - pharmacology Interleukin-6 - genetics Interleukin-6 - metabolism Macrophages - cytology Macrophages - metabolism Medical sciences Phosphatidylinositol 3-Kinases - metabolism Podocytes - drug effects Podocytes - metabolism Podocytes - pathology Proteinuria - etiology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Vertebrates: urinary system
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