Evaluation of effects of low-dose aspirin administration on urinary thromboxane metabolites in healthy dogs

Objective—To evaluate markers of in vivo platelet function (urinary 11-dehydro-thromboxane B2 [11-dehydroTXB2] and 2,3-dinorTXB2) and assess their response to administration of 2 commonly used dosages of aspirin in healthy dogs. Animals—20 healthy dogs. Procedures—Urine was collected prior to aspiri...

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Veröffentlicht in:	American journal of veterinary research 2011-08, Vol.72 (8), p.1038-1045
Hauptverfasser:	Hoh, Crystal M, Smith, Stephanie A, McMichael, Maureen A, Byron, Julie K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals aspirin Aspirin - administration & dosage Aspirin - pharmacology creatinine dogs Dogs - physiology enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - veterinary Female Male metabolites Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - pharmacology Thromboxane B2 - analogs & derivatives Thromboxane B2 - metabolism Thromboxane B2 - urine urine
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