Novel Drug OMS103HP Reduces Pain and Improves Joint Motion and Function for 90 Days After Arthroscopic Meniscectomy

Purpose This phase 2 study compared OMS103HP (Omeros, Seattle, WA) with control (lactated Ringer's) irrigation solution in patients undergoing arthroscopic partial meniscectomy. Methods This was a prospective, multicenter, double-blind, randomized, vehicle-controlled, parallel-group study. Safe...

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Veröffentlicht in:	Arthroscopy 2011-08, Vol.27 (8), p.1060-1070
Hauptverfasser:	Garrett, William E., M.D., Ph.D, Kaeding, Christopher C., M.D, ElAttrache, Neal S., M.D, Xerogeanes, John W., M.D, Hewitt, Michael S., M.D, Skrepnik, Nebojsa V., M.D., Ph.D, Papilion, John D., M.D, O'Donnell, John B., M.D, Fox, David L., M.D, Ruvuna, Francis, Ph.D, Whitaker, J. Steven, M.D., J.D, Demopulos, Gregory A., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Amitriptyline - adverse effects Amitriptyline - pharmacology Amitriptyline - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - pharmacology Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis - etiology Arthritis - prevention & control Arthroscopy Biological and medical sciences Debridement Double-Blind Method Drug Combinations Endoscopy Female Humans Investigative techniques, diagnostic techniques (general aspects) Ketoprofen - adverse effects Ketoprofen - pharmacology Ketoprofen - therapeutic use Male Medical sciences Menisci, Tibial - surgery Middle Aged Orthopedic surgery Orthopedics Oxymetazoline - adverse effects Oxymetazoline - pharmacology Oxymetazoline - therapeutic use Pain Measurement Pain, Postoperative - drug therapy Pain, Postoperative - prevention & control Prospective Studies Range of Motion, Articular - drug effects Recovery of Function - drug effects Self Report Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tibial Meniscus Injuries Young Adult
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