Sodium nitrite induces epithelial-mesenchymal transition of SMMC-7721 cells

This study is to find out the induction by sodium nitrite of epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells, SMMC-7721. After treatment of SMMC-7721 with 0.25 - 25 mmol.L-1 sodium nitrite for 48 h, the assays used include enzyme-linked immunosorbent assay (ELISA) for...

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Veröffentlicht in:	Yao hsüeh hsüeh pao 2011-05, Vol.46 (5), p.507-512
Hauptverfasser:	Wang, Yu-dong, Fu, Jian-min, Shi, Qi, Li, Yan-hong, Huang-Fu, Chao-shen
Format:	Artikel
Sprache:	chi ; jpn
Schlagworte:	Cadherins - metabolism Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Cell Line, Tumor Cell Movement Dose-Response Relationship, Drug Epithelial-Mesenchymal Transition - drug effects Humans Interleukin-6 - secretion Interleukin-8 - secretion Liver Neoplasms - metabolism Liver Neoplasms - pathology Neoplasm Invasiveness NF-kappa B - metabolism Proto-Oncogene Proteins c-akt - metabolism Sodium Nitrite - administration & dosage Sodium Nitrite - pharmacology Transforming Growth Factor beta1 - secretion Twist-Related Protein 1 - metabolism Vimentin - metabolism
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