Mechanical Properties of Single Cells by High-Frequency Time-Resolved Acoustic Microscopy

In this paper, we describe a new, high-frequency, time-resolved scanning acoustic microscope developed for studying dynamical processes in biological cells. The new acoustic microscope operates in a time-resolved mode. The center frequency is 0.86 GHz, and the pulse duration is 5 ns. With such a sho...

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Veröffentlicht in:	IEEE transactions on ultrasonics, ferroelectrics, and frequency control ferroelectrics, and frequency control, 2007-11, Vol.54 (11), p.2257-2271
Hauptverfasser:	Weiss, Eike C., Anastasiadis, Pavlos, Pilarczyk, Gotz, Lemor, Robert M., Zinin, Pavel V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic measurement Acoustic measurements Acoustic microscopes Acoustic pulses Acoustics Algorithms Biological and medical sciences Biological cells Biomechanics. Biorheology Cell Physiological Phenomena Cell physiology Elastic constants Elasticity Equipment Design Equipment Failure Analysis Frequency Fundamental and applied biological sciences. Psychology HeLa Cells Humans Image Enhancement - instrumentation Image Enhancement - methods Image Interpretation, Computer-Assisted - instrumentation Image Interpretation, Computer-Assisted - methods Impedance Mathematical models Mechanical factors Microscopy Microscopy, Acoustic - instrumentation Microscopy, Acoustic - methods Molecular and cellular biology Radio frequency Reproducibility of Results Scanning Sensitivity and Specificity Short pulses Signal resolution Signal to noise ratio Spatial resolution Stress, Mechanical Studies Tissues, organs and organisms biophysics
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