Electrospray ionization-ion mobility spectrometry as a detection system for three-phase hollow fiber microextraction technique and simultaneous determination of trimipramine and desipramine in urine and plasma samples

A novel method based on three-phase hollow fiber microextraction technique (HF-LPME) coupled with electrospray ionization-ion mobility spectrometry (ESI-IMS) was developed for the simultaneous determination of two antidepressant drugs (trimipramine and desipramine) in urine and plasma samples. The e...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2011-04, Vol.399 (10), p.3555-3564
Hauptverfasser:	Jafari, M. T, Saraji, M, Sherafatmand, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Antidepressants Antidepressive Agents - blood Antidepressive Agents - isolation & purification Antidepressive Agents - urine Biochemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Desipramine Desipramine - blood Desipramine - isolation & purification Desipramine - urine Detectors Drugs Exact sciences and technology Extraction Fibers Food Science Hafnium Humans Ion mobility spectrometry Ionization Laboratory Medicine Methods Monitoring/Environmental Analysis Original Paper Solid Phase Microextraction - instrumentation Solid Phase Microextraction - methods Spectrometric and optical methods Spectrometry Spectrometry, Mass, Electrospray Ionization - methods Spectroscopy Spectrum analysis Standard deviation Three-phase microextraction Trimipramine Trimipramine - blood Trimipramine - isolation & purification Trimipramine - urine Urine
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