Wnt Signaling and Dupuytren's Disease

Little is known about the cause of Dupuytren's disease, in which fibromatosis leads to flexion contractures of the hands and fingers. This genomic study suggests that one cause might be aberrations in the Wnt-signaling pathway. Dupuytren's disease is a benign fibromatosis of the hands and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2011-07, Vol.365 (4), p.307-317
Hauptverfasser:	Dolmans, Guido H, Werker, Paul M, Hennies, Hans C, Furniss, Dominic, Festen, Eleonora A, Franke, Andre, Franke, Lude, Becker, Kerstin, van der Vlies, Pieter, Wolffenbuttel, Bruce H, Tinschert, Sigrid, Toliat, Mohammad R, Nothnagel, Michael, Klopp, Norman, Wichmann, H.-Erich, Nürnberg, Peter, Giele, Henk, Ophoff, Roel A, Wijmenga, Cisca
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Case-Control Studies Consortia Data processing Diseases of the osteoarticular system Dupuytren Contracture - genetics Environmental factors Europe General aspects Genetic Loci Genetic markers Genetic Predisposition to Disease Genome-Wide Association Study Genomes Humans Juxtaarticular diseases. Extraarticular rhumatism Medical sciences Pathogenesis Polymorphism, Single Nucleotide Signal transduction Signal Transduction - genetics Single-nucleotide polymorphism Software packages Wnt protein Wnt Proteins - genetics Wnt Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!