The role of the gut sweet taste receptor in regulating GLP-1, PYY, and CCK release in humans

The recent identification of sweet taste receptors in the gastrointestinal tract has important implications in the control of food intake and glucose homeostasis. Lactisole can inhibit the sweet taste receptor T1R2/T1R3. The objective was to use lactisole as a probe to investigate the physiological...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2011-08, Vol.301 (2), p.E317-E325
Hauptverfasser:	Gerspach, A C, Steinert, R E, Schönenberger, L, Graber-Maier, A, Beglinger, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Appetite - drug effects Appetite - physiology Benzene Derivatives - administration & dosage Cholecystokinin - metabolism Digestive system Duodenum - physiology Eating - drug effects Eating - physiology Female Gastric Emptying - drug effects Gastric Emptying - physiology Glucagon-Like Peptide 1 - metabolism Glucose Glucose - administration & dosage Homeostasis Hormones Humans Intubation, Gastrointestinal Male Peptide YY - metabolism Peptides Receptors, G-Protein-Coupled - antagonists & inhibitors Receptors, G-Protein-Coupled - physiology Taste - drug effects Taste - physiology Young Adult
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