Possible involvement of the endocannabinoid system in memory modulation effect of general anesthetics

Abstract Amnesia is a fundamental component of a proper general anesthetic. The mechanism of anesthetic-induced amnesia remains poorly understood. Nowadays, intraoperative awareness and postoperative cognitive dysfunction are two distressing problems receiving increased attention by clinicians, pati...

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Veröffentlicht in:	Medical hypotheses 2011-08, Vol.77 (2), p.246-249
Hauptverfasser:	Ren, Yu, Xu, Ya-Jun, Tan, Zhi-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnesia - chemically induced Amygdala - metabolism Anesthetics, General - adverse effects Anesthetics, General - metabolism Cannabinoid Receptor Modulators - metabolism Cannabinoid Receptor Modulators - physiology Endocannabinoids Hippocampus - metabolism Humans Internal Medicine Models, Neurological Receptor, Cannabinoid, CB1 - metabolism
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