Analysis of Poly(amidoamine) Dendrimer Structure by UV–Vis Spectroscopy
We report a UV–vis spectroscopic study of four different types of poly(amidoamine) dendrimers. The results indicate that the degree of protonation of the interior tertiary amines of these dendrimers correlates directly to an absorption band with λmax in the range of 280–285 nm. Specifically, at low...
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| Veröffentlicht in: | Langmuir 2011-08, Vol.27 (15), p.9609-9613 |
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| creator | Pande, Surojit Crooks, Richard M |
| description | We report a UV–vis spectroscopic study of four different types of poly(amidoamine) dendrimers. The results indicate that the degree of protonation of the interior tertiary amines of these dendrimers correlates directly to an absorption band with λmax in the range of 280–285 nm. Specifically, at low pH, the tertiary amines are protonated and the 280–285 nm band is absent. However, at elevated pH, when these groups are deprotonated, this band appears. Similar results were obtained for a simple model compound. The dependence of the 280–285 nm band on the chemical state of the tertiary amines of the dendrimers was confirmed by complexing them with Pd2+ and Pt2+. In this case the band disappears, and it only reappears when the metal ions are decomplexed following reduction with BH4 –. Finally, filtration experiments showed that the absorption band between 280−285 nm arises exclusively from intact, or nearly intact, dendrimers rather than low-molecular-weight fragments. |
| doi_str_mv | 10.1021/la201882t |
| format | Article |
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The results indicate that the degree of protonation of the interior tertiary amines of these dendrimers correlates directly to an absorption band with λmax in the range of 280–285 nm. Specifically, at low pH, the tertiary amines are protonated and the 280–285 nm band is absent. However, at elevated pH, when these groups are deprotonated, this band appears. Similar results were obtained for a simple model compound. The dependence of the 280–285 nm band on the chemical state of the tertiary amines of the dendrimers was confirmed by complexing them with Pd2+ and Pt2+. In this case the band disappears, and it only reappears when the metal ions are decomplexed following reduction with BH4 –. 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The results indicate that the degree of protonation of the interior tertiary amines of these dendrimers correlates directly to an absorption band with λmax in the range of 280–285 nm. Specifically, at low pH, the tertiary amines are protonated and the 280–285 nm band is absent. However, at elevated pH, when these groups are deprotonated, this band appears. Similar results were obtained for a simple model compound. The dependence of the 280–285 nm band on the chemical state of the tertiary amines of the dendrimers was confirmed by complexing them with Pd2+ and Pt2+. In this case the band disappears, and it only reappears when the metal ions are decomplexed following reduction with BH4 –. 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The results indicate that the degree of protonation of the interior tertiary amines of these dendrimers correlates directly to an absorption band with λmax in the range of 280–285 nm. Specifically, at low pH, the tertiary amines are protonated and the 280–285 nm band is absent. However, at elevated pH, when these groups are deprotonated, this band appears. Similar results were obtained for a simple model compound. The dependence of the 280–285 nm band on the chemical state of the tertiary amines of the dendrimers was confirmed by complexing them with Pd2+ and Pt2+. In this case the band disappears, and it only reappears when the metal ions are decomplexed following reduction with BH4 –. 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| subjects | Chemistry Dendrimers - analysis Exact sciences and technology General and physical chemistry Hydrogen-Ion Concentration Materials: Nano-and Mesostructured Materials, Polymers, Gels, Liquid Crystals, Composites Molecular Structure Nanoparticles - analysis Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Palladium - chemistry Platinum - chemistry Polyamines - analysis Spectrophotometry, Ultraviolet Surface Properties |
| title | Analysis of Poly(amidoamine) Dendrimer Structure by UV–Vis Spectroscopy |
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