$Tumor Necrosis Factor-α\ Antagonist Reduces Apoptosis of Neurons and Oligodendroglia in Rat Spinal Cord Injury$

Tumor Necrosis Factor-α\ Antagonist Reduces Apoptosis of Neurons and Oligodendroglia in Rat Spinal Cord Injury

To examine the effects of a tumor necrosis factor (TNF)-α antagonist (etanercept) on rat spinal cord injury and identify a possible mechanism for its action. To elucidate the contribution of etanercept to the pathologic cascade in spinal cord injury and its possible suppression of neuronal and oligo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Spine (Philadelphia, Pa. 1976) Pa. 1976), 2011-08, Vol.36 (17), p.1350-1358
Hauptverfasser:	CHEN, Ke-Bing, UCHIDA, Kenzo, BABA, Hisatoshi, NAKAJIMA, Hideaki, YAYAMA, Takafumi, HIRAI, Takayuki, WATANABE, Shuji, RODRIGUEZ GUERRERO, Alexander, KOBAYASHI, Shigeru, MA, Wei-Ying, LIU, Shao-Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Apoptosis - drug effects Apoptosis - physiology Biological and medical sciences Cerebrospinal fluid. Meninges. Spinal cord Etanercept Immunoglobulin G - pharmacology Immunoglobulin G - therapeutic use Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences Nervous system (semeiology, syndromes) Neurology Neurons - drug effects Neurons - metabolism Neurons - pathology Oligodendroglia - drug effects Oligodendroglia - metabolism Oligodendroglia - pathology Rats Rats, Sprague-Dawley Receptors, Tumor Necrosis Factor - therapeutic use Recombinant Fusion Proteins - pharmacology Recombinant Fusion Proteins - therapeutic use Spinal Cord Injuries - drug therapy Spinal Cord Injuries - metabolism Spinal Cord Injuries - pathology Traumas. Diseases due to physical agents Tumor Necrosis Factor-alpha - antagonists & inhibitors Tumor Necrosis Factor-alpha - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!