SynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapses

J. Neurochem. (2011) 116, 1122-1137. ABSTRACT: SynArfGEF, also known as BRAG3 or IQSEC3, is a member of the brefeldin A-resistant Arf-GEF/IQSEC family and was originally identified by screening for mRNA species associated with the post-synaptic density fraction. In this study, we demonstrate that sy...

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Veröffentlicht in:	Journal of neurochemistry 2011-03, Vol.116 (6), p.1122-1137
Hauptverfasser:	Fukaya, Masahiro, Kamata, Akifumi, Hara, Yoshinobu, Tamaki, Hideaki, Katsumata, Osamu, Ito, Naoki, Takeda, Shin'ichi, Hata, Yutaka, Suzuki, Tatsuo, Watanabe, Masahiko, Harvey, Robert J, Sakagami, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing ADP-Ribosylation Factors - genetics ADP-Ribosylation Factors - metabolism ADP‐ribosylation factor 6 Animals Biological and medical sciences Brain Brain - cytology Carrier Proteins - metabolism Cell Line, Transformed Cellular biology Cerebellum Chlorocebus aethiops Dendrites Dystroglycan Dystrophin Dystrophin - metabolism Errors of metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology gephyrin Glycoproteins guanine nucleotide exchange factor Guanine Nucleotide Exchange Factors - genetics Guanine Nucleotide Exchange Factors - metabolism Guanosine Triphosphate - metabolism Guanylate Kinases Hippocampus Humans Immunoglobulin G Immunoprecipitation - methods Isolated neuron and nerve. Neuroglia Medical sciences Metabolic diseases Mice mRNA Neurochemistry Neurons Neurons - cytology Neurons - metabolism PDZ domain post‐synaptic density Protein Binding Proteins Proteins - metabolism Proteins and glycoproteins Specialization Synapses Synapses - metabolism Synapses - ultrastructure Transfection - methods Transferrin Two-Hybrid System Techniques utrophin Vertebrates: nervous system and sense organs Vesicular Inhibitory Amino Acid Transport Proteins - metabolism
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