PCB-related neurodevelopmental deficit may be transient: follow-up of a cohort at 6 years of age

Based on our own findings from a previous study we aimed to establish if cognitive deficit, shown to be induced by perinatal exposure to polychlorinated biphenyls (PCBs) at earlier ages, persists into school-age. Seventy-seven percent of a cohort last examined at 42 months of age using the Kaufman A...

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Veröffentlicht in:Environmental toxicology and pharmacology 2005-05, Vol.19 (3), p.701-706
Hauptverfasser: Winneke, Gerhard, Krämer, Ursula, Sucker, Kirsten, Walkowiak, Jens, Fastabend, Annemarie, Heinzow, Birger, Steingrüber, Hans-J.
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container_end_page 706
container_issue 3
container_start_page 701
container_title Environmental toxicology and pharmacology
container_volume 19
creator Winneke, Gerhard
Krämer, Ursula
Sucker, Kirsten
Walkowiak, Jens
Fastabend, Annemarie
Heinzow, Birger
Steingrüber, Hans-J.
description Based on our own findings from a previous study we aimed to establish if cognitive deficit, shown to be induced by perinatal exposure to polychlorinated biphenyls (PCBs) at earlier ages, persists into school-age. Seventy-seven percent of a cohort last examined at 42 months of age using the Kaufman Assessment Battery for Children were reexamined with the same test at 72 months. At this point, and contrary to the results at 30 and 42 months no adverse PCB-effects were found. However, the positive effect of the home environment became even more pronounced. Conclusion: early PCB-exposure at current environmental background levels possibly induces transient delay in cognitive development rather than irreversible deficit.
doi_str_mv 10.1016/j.etap.2004.12.040
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subjects Child development
Follow-up
Intelligence
PCBs
School age
title PCB-related neurodevelopmental deficit may be transient: follow-up of a cohort at 6 years of age
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