Change of a beneficial effect into an untoward effect by ischaemia: effect of quinidine-like drugs on vulnerability to ventricular fibrillation

The effects of three quinidine-like drugs, disopyramide, lidocaine and flecainide were investigated in anaesthetized, open-chest pigs on vulnerability to ventricular fibrillation under normal conditions and under myocardial ischaemia conditions. Vulnerability to fibrillation was evaluated by electri...

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Veröffentlicht in:Environmental toxicology and pharmacology 1996-08, Vol.2 (1), p.1-7
Hauptverfasser: Aupetit, Jean-F., Freysz, Marc, Faucon, Georges, Loufoua, Joseph, Timour, Quadiri
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Sprache:eng
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