Exposure and recovery response of isomers of HCH, metabolites of DDT and estradiol-17β in the female catfish, Heteropneustes fossilis
Abstract Effects of 40 days of exposure and 20 days of recovery response at sublethal concentration of technical grades of gamma isomer of hexachlorocyclohexane (γ-HCH, 0.025 ppm, 99.8%) and dichlorodiphenyltrichloroethane (DDT, 5.0 ppm) in tissue (liver, brain and ovary) bioconcentrations, gonadoso...
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| Veröffentlicht in: | Environmental toxicology and pharmacology 2007-11, Vol.24 (3), p.245-251 |
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| creator | Singh, Pratap B Singh, Vandana |
| description | Abstract Effects of 40 days of exposure and 20 days of recovery response at sublethal concentration of technical grades of gamma isomer of hexachlorocyclohexane (γ-HCH, 0.025 ppm, 99.8%) and dichlorodiphenyltrichloroethane (DDT, 5.0 ppm) in tissue (liver, brain and ovary) bioconcentrations, gonadosomatic index (GSI) and plasma levels of estradiol-17β (E2) have been estimated during prespawning phase in the catfish Heteropneustes fossilis (Bloch). The results indicated that the tissue bioconcentrations of both HCHs (HCH isomers) and DDTs (metabolites of DDT) in liver, brain and ovary were in preferential order (liver > brain > ovary). The GSI and plasma levels of E2 were declined in response to exposure of γ-HCH and DDT. On withdrawal of exposure of pesticide there was recovery of HCHs in exposed fish for all tissues studied, whereas DDTs exposed fish showed recovery only in liver. Recovery of E2 production was also recorded in γ-HCH exposed fish whereas very little recorded in DDT exposed fish. It is suggested that HCHs and DDTs have preferential order (liver > brain > ovary) of their tissue bioconcentrations and HCH/DDT-withdrawal-dependent recovery during studied phase. |
| doi_str_mv | 10.1016/j.etap.2007.06.001 |
| format | Article |
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The results indicated that the tissue bioconcentrations of both HCHs (HCH isomers) and DDTs (metabolites of DDT) in liver, brain and ovary were in preferential order (liver > brain > ovary). The GSI and plasma levels of E2 were declined in response to exposure of γ-HCH and DDT. On withdrawal of exposure of pesticide there was recovery of HCHs in exposed fish for all tissues studied, whereas DDTs exposed fish showed recovery only in liver. Recovery of E2 production was also recorded in γ-HCH exposed fish whereas very little recorded in DDT exposed fish. It is suggested that HCHs and DDTs have preferential order (liver > brain > ovary) of their tissue bioconcentrations and HCH/DDT-withdrawal-dependent recovery during studied phase.</description><identifier>ISSN: 1382-6689</identifier><identifier>EISSN: 1872-7077</identifier><identifier>DOI: 10.1016/j.etap.2007.06.001</identifier><identifier>PMID: 21783818</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Emergency ; Estradiol-17β ; Exposure ; HCHs and DDTs ; Heteropneustes fossilis ; Recovery ; Reproduction ; Tissue bioconcentrations</subject><ispartof>Environmental toxicology and pharmacology, 2007-11, Vol.24 (3), p.245-251</ispartof><rights>Elsevier B.V.</rights><rights>2007 Elsevier B.V.</rights><rights>Copyright © 2007 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-7ba90acf3329647b371bc130de67f3790ac7715dd328d6c618325e483acbcbea3</citedby><cites>FETCH-LOGICAL-c472t-7ba90acf3329647b371bc130de67f3790ac7715dd328d6c618325e483acbcbea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1382668907000828$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21783818$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Singh, Pratap B</creatorcontrib><creatorcontrib>Singh, Vandana</creatorcontrib><title>Exposure and recovery response of isomers of HCH, metabolites of DDT and estradiol-17β in the female catfish, Heteropneustes fossilis</title><title>Environmental toxicology and pharmacology</title><addtitle>Environ Toxicol Pharmacol</addtitle><description>Abstract Effects of 40 days of exposure and 20 days of recovery response at sublethal concentration of technical grades of gamma isomer of hexachlorocyclohexane (γ-HCH, 0.025 ppm, 99.8%) and dichlorodiphenyltrichloroethane (DDT, 5.0 ppm) in tissue (liver, brain and ovary) bioconcentrations, gonadosomatic index (GSI) and plasma levels of estradiol-17β (E2) have been estimated during prespawning phase in the catfish Heteropneustes fossilis (Bloch). The results indicated that the tissue bioconcentrations of both HCHs (HCH isomers) and DDTs (metabolites of DDT) in liver, brain and ovary were in preferential order (liver > brain > ovary). The GSI and plasma levels of E2 were declined in response to exposure of γ-HCH and DDT. On withdrawal of exposure of pesticide there was recovery of HCHs in exposed fish for all tissues studied, whereas DDTs exposed fish showed recovery only in liver. Recovery of E2 production was also recorded in γ-HCH exposed fish whereas very little recorded in DDT exposed fish. It is suggested that HCHs and DDTs have preferential order (liver > brain > ovary) of their tissue bioconcentrations and HCH/DDT-withdrawal-dependent recovery during studied phase.</description><subject>Emergency</subject><subject>Estradiol-17β</subject><subject>Exposure</subject><subject>HCHs and DDTs</subject><subject>Heteropneustes fossilis</subject><subject>Recovery</subject><subject>Reproduction</subject><subject>Tissue bioconcentrations</subject><issn>1382-6689</issn><issn>1872-7077</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFkk9u1DAUhyMEoqVwARbIK9g04dnO2B4JIaFpYZAqsaCsLcd-UT0kcbCTirlAD9SDcCacTmHBoqz8ZH-_5z-fi-IlhYoCFW93FU5mrBiArEBUAPRRcUyVZKUEKR_nmitWCqHWR8WzlHYZWHGunhZHjErFFVXHxc35zzGkOSIxgyMRbbjGuM9FGsOQkISW-BR6jGkpt5vtKenzrk3o_IR3c2dnl3dZTFM0zoeupPLXLfEDma6QtNibDok1U-vT1SnZ4oQxjAPOacm3ISXf-fS8eNKaLuGL-_Gk-Pbx_HKzLS--fPq8-XBR2lqyqZSNWYOxLedsLWrZcEkbSzk4FLLlclmTkq6c40w5YQVVnK2wVtzYxjZo-Enx5tB3jOHHnI-se58sdp0ZMMxJK7mmwGu-yuTrB0kGQjAq1H9BWqsaVC0yyA6gjfnWEVs9Rt-buNcU9CJU7_QiVC9CNQidfeXQq_vuc9Oj-xv5YzAD7w4A5me79hh1sh4Hi85nm5N2wT_c__0_cdv5wVvTfcc9pl2Y45CFaKoT06C_Ll9q-VEgAUAxxX8Dl7bH1A</recordid><startdate>20071101</startdate><enddate>20071101</enddate><creator>Singh, Pratap B</creator><creator>Singh, Vandana</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7TV</scope><scope>7U7</scope><scope>7X8</scope></search><sort><creationdate>20071101</creationdate><title>Exposure and recovery response of isomers of HCH, metabolites of DDT and estradiol-17β in the female catfish, Heteropneustes fossilis</title><author>Singh, Pratap B ; Singh, Vandana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-7ba90acf3329647b371bc130de67f3790ac7715dd328d6c618325e483acbcbea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Emergency</topic><topic>Estradiol-17β</topic><topic>Exposure</topic><topic>HCHs and DDTs</topic><topic>Heteropneustes fossilis</topic><topic>Recovery</topic><topic>Reproduction</topic><topic>Tissue bioconcentrations</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Singh, Pratap B</creatorcontrib><creatorcontrib>Singh, Vandana</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Environmental toxicology and pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Singh, Pratap B</au><au>Singh, Vandana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Exposure and recovery response of isomers of HCH, metabolites of DDT and estradiol-17β in the female catfish, Heteropneustes fossilis</atitle><jtitle>Environmental toxicology and pharmacology</jtitle><addtitle>Environ Toxicol Pharmacol</addtitle><date>2007-11-01</date><risdate>2007</risdate><volume>24</volume><issue>3</issue><spage>245</spage><epage>251</epage><pages>245-251</pages><issn>1382-6689</issn><eissn>1872-7077</eissn><abstract>Abstract Effects of 40 days of exposure and 20 days of recovery response at sublethal concentration of technical grades of gamma isomer of hexachlorocyclohexane (γ-HCH, 0.025 ppm, 99.8%) and dichlorodiphenyltrichloroethane (DDT, 5.0 ppm) in tissue (liver, brain and ovary) bioconcentrations, gonadosomatic index (GSI) and plasma levels of estradiol-17β (E2) have been estimated during prespawning phase in the catfish Heteropneustes fossilis (Bloch). The results indicated that the tissue bioconcentrations of both HCHs (HCH isomers) and DDTs (metabolites of DDT) in liver, brain and ovary were in preferential order (liver > brain > ovary). The GSI and plasma levels of E2 were declined in response to exposure of γ-HCH and DDT. On withdrawal of exposure of pesticide there was recovery of HCHs in exposed fish for all tissues studied, whereas DDTs exposed fish showed recovery only in liver. Recovery of E2 production was also recorded in γ-HCH exposed fish whereas very little recorded in DDT exposed fish. It is suggested that HCHs and DDTs have preferential order (liver > brain > ovary) of their tissue bioconcentrations and HCH/DDT-withdrawal-dependent recovery during studied phase.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>21783818</pmid><doi>10.1016/j.etap.2007.06.001</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 1382-6689 |
| ispartof | Environmental toxicology and pharmacology, 2007-11, Vol.24 (3), p.245-251 |
| issn | 1382-6689 1872-7077 |
| language | eng |
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| source | Elsevier ScienceDirect Journals |
| subjects | Emergency Estradiol-17β Exposure HCHs and DDTs Heteropneustes fossilis Recovery Reproduction Tissue bioconcentrations |
| title | Exposure and recovery response of isomers of HCH, metabolites of DDT and estradiol-17β in the female catfish, Heteropneustes fossilis |
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