Epithelium-linked smooth muscle hyperresponsiveness in ferret tracheae exposed to acrolein

The effects of acrolein exposure on tissue uptake and airway responses to substance P (SP) and nitroprusside (NIP) were determined in excised ferret tracheae exposed for 60 min to a constant flow of air or 0.3 and 3.5 ppm acrolein-air mixtures. Histological examination indicated that whereas the epi...

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Veröffentlicht in:Environmental toxicology and pharmacology 1996-08, Vol.2 (1), p.49-57
Hauptverfasser: Ben-Jebria, Abdellaziz, Crozet, Yves, Eskew, Mary Lou, Ultman, James S.
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Sprache:eng
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