SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl−-dependent transporters) comprise a group of nine sodium- and chloride-dependent plasma membrane transporters for the monoamine ne...

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Veröffentlicht in:	Pharmacological reviews 2011-09, Vol.63 (3), p.585-640
Hauptverfasser:	Kristensen, Anders S., Andersen, Jacob, Jørgensen, Trine N., Sørensen, Lena, Eriksen, Jacob, Loland, Claus J., Strømgaard, Kristian, Gether, Ulrik
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport Systems, Neutral - agonists Amino Acid Transport Systems, Neutral - antagonists & inhibitors Amino Acid Transport Systems, Neutral - chemistry Amino Acid Transport Systems, Neutral - metabolism Amino acids Animals Anxiety Attention deficit hyperactivity disorder Brain Cocaine Drug abuse Epilepsy gamma -Aminobutyric acid Gene families Homeostasis Humans Ligands Membrane Microdomains - metabolism Mental disorders Molecular Targeted Therapy monoamines Nerve Tissue Proteins - agonists Nerve Tissue Proteins - antagonists & inhibitors Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - metabolism Neurons - drug effects Neurons - metabolism Neurotransmitters Norepinephrine Organ Specificity Pharmacology Plasma Membrane Neurotransmitter Transport Proteins - agonists Plasma Membrane Neurotransmitter Transport Proteins - antagonists & inhibitors Plasma Membrane Neurotransmitter Transport Proteins - chemistry Plasma Membrane Neurotransmitter Transport Proteins - metabolism Plasma membranes Protein Isoforms - agonists Protein Isoforms - antagonists & inhibitors Protein Isoforms - chemistry Protein Isoforms - metabolism Protein Processing, Post-Translational Protein Transport Serotonin Solutes Structure-function relationships Synaptic Transmission - drug effects
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