Dependence of collision-induced dissociation energy on molecular degrees of freedom as a means to assess relative binding affinity in multivalent complexes

In collision‐induced dissociation mass spectrometry experiments, the collision energy required for dissociation linearly depends on the degrees of freedom in the precursor ion. The magnitude of the slope of this relationship previously has been shown to qualitatively correlate to the relative bindin...

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Veröffentlicht in:Rapid communications in mass spectrometry 2011-08, Vol.25 (16), p.2299-2306
Hauptverfasser: Huffman, Carmen L., Williams, Melissa Lee, Benoist, D. Michelle, Overstreet, Richard E., Jellen-McCullough, Emily E.
Format: Artikel
Sprache:eng
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