The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany

The use of fish embryos is gaining popularity for research in the area of toxicology and teratology. Particularly embryos of the zebrafish offer an array of different applications ranging from regulatory testing to mechanistic research. For this reason a consortium of two research centres and a comp...

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Veröffentlicht in:Reproductive toxicology (Elmsford, N.Y.) N.Y.), 2011-05, Vol.31 (4), p.585-588
Hauptverfasser: Busch, Wibke, Duis, Karen, Fenske, Martina, Maack, Gerd, Legler, Juliette, Padilla, Stephanie, Strähle, Uwe, Witters, Hilda, Scholz, Stefan
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container_end_page 588
container_issue 4
container_start_page 585
container_title Reproductive toxicology (Elmsford, N.Y.)
container_volume 31
creator Busch, Wibke
Duis, Karen
Fenske, Martina
Maack, Gerd
Legler, Juliette
Padilla, Stephanie
Strähle, Uwe
Witters, Hilda
Scholz, Stefan
description The use of fish embryos is gaining popularity for research in the area of toxicology and teratology. Particularly embryos of the zebrafish offer an array of different applications ranging from regulatory testing to mechanistic research. For this reason a consortium of two research centres and a company with the support of the COST Action EuFishBiomed has organised the Workshop “The zebrafish embryo model in toxicology and teratology”, in Karlsruhe, Germany, 2nd–3rd September 2010. The workshop aimed at bringing together experts from different areas of toxicology using the (zebra)fish embryo and stimulating networking between scientists and representatives from regulatory bodies, research institutions and industry. Recent findings, presented in various platform presentations in the area of regulatory toxicity, high throughput screening, toxicogenomics, as well as environmental and human risk assessment are highlighted in this meeting report. Furthermore, the constraints and possibilities of the model as discussed at the workshop are described. A follow up-meeting was appreciated by the about 120 participants and is planned for 2012.
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subjects 3Rs
Abnormalities, Drug-Induced - etiology
Abnormalities, Drug-Induced - genetics
Alternatives to animal testing
Animals
Development
Embryo, Nonmammalian - abnormalities
Embryo, Nonmammalian - drug effects
Embryo, Nonmammalian - pathology
Fish embryo
Gene Expression Regulation, Developmental - drug effects
High throughput screening
High-Throughput Screening Assays - standards
Humans
Regulatory toxicology
Risk Assessment
Teratogens - toxicity
Toxicity Tests - standards
Toxicogenetics
Toxicogenomics
Zebrafish
Zebrafish - embryology
Zebrafish - genetics
title The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany
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