Loss of Drosophila Myb interrupts the progression of chromosome condensation

Completion of chromosome condensation is required before segregation during the mitotic cell cycle to ensure the transmission of genetic material with high fidelity in a timely fashion. In many eukaryotes this condensation is regulated by phosphorylation of histone H3 on Ser 10 (H3S10). This phospho...

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Veröffentlicht in:	Nature cell biology 2007-05, Vol.9 (5), p.581-587
Hauptverfasser:	Manak, J. Robert, Wen, Hong, Van, Tran, Andrejka, Laura, Lipsick, Joseph S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Cancer Research Cell Biology Cell cycle Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell division Cell Nucleus - metabolism Cellular proteins Chromatin Assembly and Disassembly Chromosomes Chromosomes - metabolism Cloning Developmental Biology DNA methylation Drosophila Drosophila - embryology Drosophila - genetics Drosophila - physiology Drosophila Proteins - deficiency Drosophila Proteins - genetics Drosophila Proteins - metabolism Euchromatin - metabolism Genetic aspects Genetic engineering Health aspects Heterochromatin - metabolism Histones - metabolism Insects Larva - physiology letter Life Sciences Mitosis - physiology Mutation Phosphorylation Premature chromosome condensation Proteins Proto-Oncogene Proteins c-myb - deficiency Proto-Oncogene Proteins c-myb - genetics Proto-Oncogene Proteins c-myb - metabolism Serine - metabolism Signal transduction Stem Cells
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