Changes of motor abilities during ontogenetic development in Lurcher mutant mice

Abstract Lurcher mutant mice represent a natural model of olivocerebellar degeneration. This degeneration is caused by a mutation of the gene for the δ2 glutamate receptor. Lurcher mutants suffer from cerebellar ataxia and cognitive functions deficiency as a consequence of excitotoxic apoptosis of P...

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Veröffentlicht in:	Neuroscience 2010-07, Vol.168 (3), p.646-651
Hauptverfasser:	MARKVARTOVA, V, CENDELIN, J, VOZEH, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Apoptosis Biological and medical sciences cerebellar ataxia Disease Models, Animal Female Fundamental and applied biological sciences. Psychology Male Mice Mice, Mutant Strains Motor Skills Neurology olivocerebellar degeneration Olivopontocerebellar Atrophies - genetics Olivopontocerebellar Atrophies - physiopathology Reaction Time Vertebrates: nervous system and sense organs
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