Medicinal plants and antioxidants: What do we learn from cell culture and Caenorhabditis elegans studies?

Traditional medicinal plants have a long history of therapeutic use. The beneficial health effects of medicinal plants rich in polyphenols are often attributed to their potent antioxidant activities, as established in vitro, since diets rich in polyphenols are epidemiologically associated with a dec...

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Veröffentlicht in:Biochemical and biophysical research communications 2010-03, Vol.394 (1), p.1-5
Hauptverfasser: Tang, Soon Yew, Halliwell, Barry
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Halliwell, Barry
description Traditional medicinal plants have a long history of therapeutic use. The beneficial health effects of medicinal plants rich in polyphenols are often attributed to their potent antioxidant activities, as established in vitro, since diets rich in polyphenols are epidemiologically associated with a decreased incidence of age-related diseases in humans. However, medicinal plants may also exert pro-oxidant effects that up-regulate endogenous protective enzymes. Care is needed when studying the biological effects of medicinal plants in cell culture because some polyphenols oxidize readily in culture media. This review summarizes the data we have obtained from in vitro and in vivo (Caenorhabditis elegans) studies examining the diverse effects of traditional medicinal plants and their modes of action.
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subjects Animals
Antioxidants
Antioxidants - chemistry
Antioxidants - pharmacology
Caenorhabditis elegans
Caenorhabditis elegans - cytology
Caenorhabditis elegans - drug effects
Cell culture
Cell Culture Techniques
Drug Evaluation, Preclinical
Oxidative Stress
Plants, Medicinal - chemistry
Polyphenols
Traditional medicinal plants
title Medicinal plants and antioxidants: What do we learn from cell culture and Caenorhabditis elegans studies?
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