Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

Abstract Homeostatic control of the endoplasmic reticulum (ER) both as the site for protein handling (synthesis, folding, trafficking, disaggregation and degradation) and as a Ca2+ store is of crucial importance for correct functioning of the cell. Disturbance of the homeostatic control mechanisms l...

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Veröffentlicht in:	Cell calcium (Edinburgh) 2010-04, Vol.47 (4), p.297-314
Hauptverfasser:	Sammels, Eva, Parys, Jan B, Missiaen, Ludwig, De Smedt, Humbert, Bultynck, Geert
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Autophagy Ca2+ channels Ca2+ leak Ca2+ signaling Calcium - metabolism Calcium Channels - metabolism Calcium Signaling Cell death Endoplasmic Reticulum - metabolism ER stress Humans Intracellular Ca2+ store Ion Pumps - metabolism Organelle Size Unfolded Protein Response
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