Asymmetric synthesis of quaternary α-amino acid derivatives and their fluorinated analogues

In this work, we describe the asymmetric synthesis of a series of fluorinated and non-fluorinated quaternary α-amino acid derivatives. This methodology involves the diastereoselective addition of chiral 2- p -tolylsulfinyl benzylcarbanions to either imines containing a 2-furyl moiety or trifluoromet...

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