T and B lymphocyte abnormalities in bone marrow biopsies of common variable immunodeficiency

In common variable immunodeficiency (CVID) defects in early stages of B-cell development, bone marrow (BM) plasma cells and T lymphocytes have not been studied systematically. Here we report the first morphologic and flow cytometric study of B- and T-cell populations in CVID BM biopsies and aspirate...

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Veröffentlicht in:	Blood 2011-07, Vol.118 (2), p.309-318
Hauptverfasser:	Ochtrop, Manuella L. Gomes, Goldacker, Sigune, May, Annette M., Rizzi, Marta, Draeger, Ruth, Hauschke, Dieter, Stehfest, Claudia, Warnatz, Klaus, Goebel, Heike, Technau-Ihling, Katja, Werner, Martin, Salzer, Ulrich, Eibel, Hermann, Schlesier, Michael, Peter, Hans Hartmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged B-Lymphocytes - pathology Biological and medical sciences Biopsy Bone Marrow Cells - pathology Cohort Studies Common Variable Immunodeficiency - immunology Common Variable Immunodeficiency - pathology Female Hematologic and hematopoietic diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Lymphocyte Count Male Medical sciences Middle Aged T-Lymphocytes - pathology Young Adult
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