Epicardial Fat Volume in Patients With Left Ventricular Systolic Dysfunction

Epicardial adipose tissue has been linked to cardiovascular metabolism and inflammation and has been shown to predict prevalence and progression of coronary artery disease. Only limited data are available on the role of epicardial fat in patients with heart failure (HF). We analyzed cardiac adiposit...

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Veröffentlicht in:	The American journal of cardiology 2011-08, Vol.108 (3), p.397-401
Hauptverfasser:	Khawaja, Tuba, MD, Greer, Christine, BS, Chokshi, Aalap, BS, Chavarria, Nelson, MD, Thadani, Samir, MD, Jones, Meaghan, BS, Schaefle, Kenneth, BS, Bhatia, Ketan, BS, Collado, J. Elias, MD, Shimbo, Daichi, MD, Einstein, Andrew J., MD, PhD, Schulze, P. Christian, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, White - diagnostic imaging Adipose Tissue, White - physiopathology Adult Aged Biological and medical sciences Biomarkers Body Mass Index Calcinosis - diagnostic imaging Calcinosis - physiopathology Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular disease Cohort Studies Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Coronary vessels Female Heart Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Kidney Function Tests Male Medical sciences Middle Aged Pericardium - diagnostic imaging Pericardium - physiopathology Prognosis Reference Values Stroke Volume - physiology Tomography Tomography, X-Ray Computed Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:	Epicardial adipose tissue has been linked to cardiovascular metabolism and inflammation and has been shown to predict prevalence and progression of coronary artery disease. Only limited data are available on the role of epicardial fat in patients with heart failure (HF). We analyzed cardiac adiposity and its relation to markers of morbidity and clinical outcome in patients with normal and impaired left ventricular (LV) function. Epicardial fat volume (EFV) and coronary artery calcium were measured in 381 patients (210 women and 171 men, mean age 55 ± 10 years) who underwent low-dose computed tomography. HF was defined by LV ejection fraction (EF) 55% (mean 63 ± 6) and 60 patients had an EF
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2011.03.058