CTNNB1 Gene Mutations, Pituitary Transcription Factors, and MicroRNA Expression Involvement in the Pathogenesis of Adamantinomatous Craniopharyngiomas

Genes involved in formation/development of the adenohypophysis, CTNNB1 gene, and microRNAs might be implicated in the craniopharyngioma pathogenesis. The objective of this study is to perform the molecular analysis of HESX1 , PROP1 , POU1F1 , and CTNNB1 genes and evaluate a panel of miRNA expression...

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Veröffentlicht in:	Hormones & cancer 2010-08, Vol.1 (4), p.187-196
Hauptverfasser:	Campanini, Marina Lanciotti, Colli, Leandro Machado, Paixao, Beatriz Maria Carvalho, Cabral, Tatiana Pereira Freitas, Amaral, Fernando Colbari, Machado, Helio Rubens, Neder, Luciano Serafin, Saggioro, Fabiano, Moreira, Ayrton Custodio, Antonini, Sonir Roberto Rauber, de Castro, Margaret
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged beta Catenin - genetics Cell Biology Child Craniopharyngioma - genetics Craniopharyngioma - pathology Endocrinology Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Frequency Genetic Predisposition to Disease Genotype Homeodomain Proteins - genetics Humans Internal Medicine Male Medicine Medicine & Public Health Microbiology MicroRNAs - genetics Middle Aged Mutation Oncology Pituitary Gland - metabolism Pituitary Gland - pathology Pituitary Neoplasms - genetics Pituitary Neoplasms - pathology Polymorphism, Single Nucleotide Systems Biology Transcription Factor Pit-1 - genetics Transcription Factors - genetics Young Adult
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